FNIP1 Rabbit pAb
Catalog No:AB-A15552
Manufacturer:ABclonal
Synonyms:FNIP1
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | FNIP1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the folliculin-interacting protein family. The encoded protein binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK) and be involved in cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. A homologous binding partner of this protein, folliculin-interacting protein 2, has similar binding activities and may suggest functional redundancy within this protein family. Both folliculin-interacting proteins have also been shown to bind the molecular chaperone heat shock protein-90 (Hsp90) and they may function as a co-chaperones in the stabilization of tumor suppressor folliculin which is a target of Hsp90 chaperone activity. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-350 of human FNIP1 (NP_588613.2). |
Gene ID: | 96459 |
Swiss prot: | Q8TF40 |
Molecular weight: | 56kDa/127kDa/130kDa |
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