.jpg)
Western blot analysis of extracts from normal (control) and CDK6 knockout (KO) HeLa cells, using CDK6 antibody (A1545) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
[KO Validated] CDK6 Rabbit pAb
Catalog No：AB-A1545
Manufacturer：ABclonal
Synonyms：CDK6;MCPH12;PLSTIRE
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€110,00 – €425,00
| Product Name: | [KO Validated] CDK6 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human CDK6 (NP_001250.1). |
| Gene ID: | 1021 |
| Swiss prot: | Q00534 |
| Molecular weight: | 36kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-A0887
Manufacturer：ABclonal
Synonyms：BAF190;BAF190A;BRG1;CSS4;MRD16;RTPS2;SNF2;SNF2L4;SNF2LB;SWI2;hSNF2b;SMARCA4
Applications：WB,IHC,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0816
Manufacturer：ABclonal
Synonyms：IIAE7;IRF3
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0746
Manufacturer：ABclonal
Synonyms：CCND3;cyclin D3;Cyclin D3
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0707
Manufacturer：ABclonal
Synonyms：MECP2;AUTSX3;MRX16;MRX79;MRXS13;MRXSL;PPMX;RS;RTS;RTT
Applications：WB,IHC
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0561
Manufacturer：ABclonal
Synonyms：ANOP3;MCOPS3;SOX2;SRY-box 2
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0281
Manufacturer：ABclonal
Synonyms：CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;casp9;Caspase 9
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00