Western blot analysis of extracts of various cell lines, using MYOF antibody (A15427) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 2s.
MYOF Rabbit pAb
Catalog No:AB-A15427
Manufacturer:ABclonal
Synonyms:MYOF;FER1L3;myoferlin
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MYOF Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1). |
Gene ID: | 26509 |
Swiss prot: | Q9NZM1 |
Molecular weight: | 17kDa/46kDa/49kDa/179kDa/229kDa/233kDa/234kDa |
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