UPF1/RENT1 Rabbit pAb
Catalog No:AB-A1521
Manufacturer:ABclonal
Synonyms:UPF1;HUPF1;NORF1;RENT1;pNORF1;smg-2
Applications:WB,IF,IP
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | UPF1/RENT1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2). |
Gene ID: | 5976 |
Swiss prot: | Q92900 |
Molecular weight: | 123kDa/124kDa |
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