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Western blot analysis of extracts of various cell lines, using PBX1 antibody (A0124) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
PBX1 Rabbit pAb
Catalog No：AB-A0124
Manufacturer：ABclonal
Synonyms：PBX1
Applications：WB
Reactivity：Human,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PBX1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PBX1 (NP_002576.1). |
| Gene ID: | 5087 |
| Swiss prot: | P40424 |
| Molecular weight: | 38kDa/46kDa |
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