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Western blot analysis of extracts of various cell lines, using BRE antibody (A15122) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 60s.
BRE Rabbit pAb
Catalog No：AB-A15122
Manufacturer：ABclonal
Synonyms：BRE;BRCC4;BRCC45
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | BRE Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-229 of human BRE (NP_954661.1). |
| Gene ID: | 9577 |
| Swiss prot: | Q9NXR7 |
| Molecular weight: | 42kDa/43kDa/46kDa |
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