Western blot analysis of extracts of various cell lines, using CDC23 antibody (A15116) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
CDC23 Rabbit pAb
Catalog No:AB-A15116
Manufacturer:ABclonal
Synonyms:CDC23;ANAPC8;APC8;CUT23
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CDC23 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CDC23 (NP_004652.2). |
Gene ID: | 8697 |
Swiss prot: | Q9UJX2 |
Molecular weight: | 16kDa/55kDa/68kDa |
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