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Western blot analysis of extracts of various cell lines, using PDE1C antibody (A15078) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
PDE1C Rabbit pAb
Catalog No：AB-A15078
Manufacturer：ABclonal
Synonyms：PDE1C;Hcam3;cam-PDE 1C;hCam-3;cam-PDE1C
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PDE1C Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes an enzyme that belongs to the 3’5′-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5′-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 435-634 of human PDE1C (NP_001177985.1). |
| Gene ID: | 5137 |
| Swiss prot: | Q14123 |
| Molecular weight: | 72kDa/80kDa/86kDa |
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