Western blot analysis of extracts of various cell lines, using GP6 antibody (A14999) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
GP6 Rabbit pAb
Catalog No:AB-A14999
Manufacturer:ABclonal
Synonyms:GP6;BDPLT11;GPIV;GPVI
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | GP6 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human GP6 (NP_057447.4). |
Gene ID: | 51206 |
Swiss prot: | Q9HCN6 |
Molecular weight: | 35kDa/36kDa/67kDa |
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