Western blot analysis of extracts of various cell lines, using VEGFR1 antibody (A0058) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
VEGFR1 Rabbit pAb
Catalog No:AB-A0058
Manufacturer:ABclonal
Synonyms:FLT;FLT-1;VEGFR-1;VEGFR1;FLT1
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | VEGFR1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1100-1200 of human VEGFR1 (NP_002010.2). |
Gene ID: | 2321 |
Swiss prot: | P17948 |
Molecular weight: | 39kDa/41kDa/52- 82kDa/150kDa |
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