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Western blot analysis of extracts of various cell lines, using IBTK antibody (A14866) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
IBTK Rabbit pAb
Catalog No：AB-A14866
Manufacturer：ABclonal
Synonyms：IBTK;BTBD26;BTKI
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | IBTK Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK’s kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human IBTK (NP_056340.2). |
| Gene ID: | 25998 |
| Swiss prot: | Q9P2D0 |
| Molecular weight: | 26kDa/133kDa/150kDa |
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