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Immunohistochemistry of paraffin-embedded human lung using RB1 antibody (A14775) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse lung using RB1 antibody (A14775) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using RB1 antibody (A14775) at dilution of 1:100 (40x lens).
RB Rabbit pAb
Catalog No：AB-A14775
Manufacturer：ABclonal
Synonyms：OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Applications：IHC
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RB Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 649-928 of human RB (NP_000312.2). |
| Gene ID: | 5925 |
| Swiss prot: | P06400 |
| Molecular weight: | 106kDa |
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