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Western blot analysis of extracts of various cell lines, using XPD/XPD/ERCC2 antibody (A14563) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
XPD/ERCC2 Rabbit pAb
Catalog No：AB-A14563
Manufacturer：ABclonal
Synonyms：ERCC2;COFS2;EM9;TFIIH;TTD;TTD1;XPD
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | XPD/ERCC2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human XPD/XPD/ERCC2 (NP_001124339.1). |
| Gene ID: | 2068 |
| Swiss prot: | P18074 |
| Molecular weight: | 46kDa/86kDa |
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