Western blot analysis of extracts of 293T cells, using CISH antibody (A14527) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 15s.
CISH Rabbit pAb
Catalog No:AB-A14527
Manufacturer:ABclonal
Synonyms:CISH;BACTS2;CIS;CIS-1;G18;SOCS
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CISH Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1). |
Gene ID: | 1154 |
Swiss prot: | Q9NSE2 |
Molecular weight: | 28kDa/29kDa/30kDa |
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