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Western blot analysis of extracts of various cell lines, using GNRHR antibody (A14487) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
GNRHR Rabbit pAb
Catalog No：AB-A14487
Manufacturer：ABclonal
Synonyms：GNRHR;GNRHR1;GRHR;HH7;LHRHR;LRHR
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | GNRHR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5′ region and multiple polyA signals in the 3′ region have been identified for this gene. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GNRHR (NP_000397.1). |
| Gene ID: | 2798 |
| Swiss prot: | P30968 |
| Molecular weight: | 27kDa/37kDa |
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