Western blot analysis of extracts of various cell lines, using CBS Polyclonal Antibody (A1427) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
CBS Rabbit pAb
Catalog No:AB-A1427
Manufacturer:ABclonal
Synonyms:CBS;HIP4
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CBS Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of human CBS (NP_000062.1). |
Gene ID: | 875 |
Swiss prot: | P35520 |
Molecular weight: | 60kDa/61kDa |
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