Western blot analysis of extracts of various cell lines, using CASR antibody (A1426) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
CASR Rabbit pAb
Catalog No:AB-A1426
Manufacturer:ABclonal
Synonyms:CASR;CAR;EIG8;FHH;FIH;GPRC2A;HHC;HHC1;HYPOC1;NSHPT;PCAR1;hCasR
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CASR Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 874-1088 of human CASR (NP_001171536.1). |
Gene ID: | 846 |
Swiss prot: | P41180 |
Molecular weight: | 120kDa/121kDa |
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