RNF8 Rabbit pAb
Catalog No:AB-A14083
Manufacturer:ABclonal
Synonyms:RNF8;hRNF8
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RNF8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNF8 (NP_003949.1). |
Gene ID: | 9025 |
Swiss prot: | O76064 |
Molecular weight: | 10kDa/50kDa/55kDa |
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