Western blot analysis of extracts of various cell lines, using PTPN22 antibody (A1406) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
PTPN22 Rabbit pAb
Catalog No:AB-A1406
Manufacturer:ABclonal
Synonyms:PTPN22;LYP;LYP1;LYP2;PEP;PTPN22.5;PTPN22.6;PTPN8
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PTPN22 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves’ disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_036543.4). |
Gene ID: | 26191 |
Swiss prot: | Q9Y2R2 |
Molecular weight: | 20kDa/75kDa/78kDa/85kDa/88kDa/91kDa |
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