Western blot analysis of extracts of HeLa cells, using Galactosidase alpha (Galactosidase alpha (GLA)) antibody (A13987) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
Galactosidase alpha (GLA) Rabbit pAb
Catalog No:AB-A13987
Manufacturer:ABclonal
Synonyms:GLA;GALA
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Galactosidase alpha (GLA) Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (Galactosidase alpha (GLA)) (NP_000160.1). |
Gene ID: | 2717 |
Swiss prot: | P06280 |
Molecular weight: | 48kDa |
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