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Western blot analysis of extracts of various cell lines, using CTLA4 antibody (A13965) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
CTLA4 Rabbit pAb
Catalog No：AB-A13965
Manufacturer：ABclonal
Synonyms：CTLA4;ALPS5;CD;CD152;CELIAC3;CTLA-4;GRD4;GSE;IDDM12
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | CTLA4 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 49-223 of human CTLA4 (NP_005205.2). |
| Gene ID: | 1493 |
| Swiss prot: | P16410 |
| Molecular weight: | 6kDa/8kDa/19kDa/24kDa |
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