7-Chloro-4-(piperazin-1-yl)quinoline [Cas No. 837-52-5]
Catalog No:TA-Fr13587
Manufacturer:TargetMol
CAS No.:837-52-5
Formula:C13H14ClN3
MWt:247.73
Product Name: | 7-Chloro-4-(piperazin-1-yl)quinoline |
Category: | Biochemicals > Small Compounds |
Description: | 7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively [1]. |
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