Phosphatase Inhibitor Cocktail I (100× ddH2O)
Catalog No：TA-C0002
Manufacturer：TargetMol
CAS No.：C0002
€29,00 – €1.236,00
| Product Name: | Phosphatase Inhibitor Cocktail I (100× ddH2O) |
| Category: | Cell Based Assays |
| Description: | It is easy for the proteins to be degraded or dephosphorylated during in vitro extraction procedure, which could cause an inaccurate result of protein expression detection. Therefore, adding protease inhibitors or phosphatase inhibitors into the extracts would be an effective method to prevent degradation and dephosphorylation of protein. The phosphatase inhibitor mixture can effectively inhibit the dephosphorylation of common phosphatases on proteins and maintain the original phosphorylation state of proteins. |
| Publications: | 1. Ren Y, Wang A, Zhang B, et al.Human cytomegalovirus UL36 inhibits IRF3-dependent immune signaling to counterbalance its immunoenhancement as apoptotic inhibitor.Science Advances.2023, 9(40): eadi6586. 2. Li B, Yang T, Liu J, et al.Genetically engineered PD-1 displaying nanovesicles for synergistic checkpoint blockades and chemo-metabolic therapy against non-small cell lung cancer.Acta Biomaterialia.2023, 161: 184-200. 3. Tabasum S, Thapa D, Giobbie-Hurder A, et al.EDIL3 as an angiogenic target of immune exclusion following checkpoint blockade.Cancer Immunology Research.2023 4. Liu L, Lei Y, Chen W, et al.In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer.Cell & Bioscience.2022, 12(1): 1-21. 5. Li J, Dang P, Li Z, et al.Peroxisomal ERK mediates Akh/glucagon action and glycemic control.Cell Reports.2023, 42(10). 6. Wu K, Zhang Y, Liu Y, et al.Phosphorylation of UHRF2 affects malignant phenotypes of HCC and HBV replication by blocking DHX9 ubiquitylation.Cell Death Discovery.2023, 9(1): 27. 7. Wang C, Wang T, Hu R, et al.9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.Journal of Virology.2023: e01984-22. 8. Pirri C, Caroccia B, Angelini A, et al.A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP).International Journal of Molecular Sciences.2023, 24(20): 15389. 9. Wang C, Hu R, Wang T, et al.A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605. 10. Yin H, Fu X Y, Gao H Y, et al.Design, synthesis and anticancer evaluation of novel oncolytic peptide-chlorambucil conjugates.Bioorganic Chemistry.2023: 106674. |
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