Western blot analysis of extracts of various cell lines, using ADRA2A antibody (A13941) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 20s.
ADRA2A Rabbit pAb
Catalog No:AB-A13941
Manufacturer:ABclonal
Synonyms:ADRA2A;ADRA2;ADRA2R;ADRAR;ALPHA2AAR;ZNF32
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ADRA2A Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2A (NP_000672.3). |
Gene ID: | 150 |
Swiss prot: | P08913 |
Molecular weight: | 48kDa |
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