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Western blot analysis of extracts of various cell lines, using SNAP23 antibody (A13909) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 2min.
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Immunohistochemistry of paraffin-embedded human appendix using SNAP23 antibody (A13909) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat lymph node using SNAP23 antibody (A13909) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using SNAP23 antibody (A13909) at dilution of 1:100 (40x lens).
SNAP23 Rabbit pAb
Catalog No：AB-A13909
Manufacturer：ABclonal
Synonyms：SNAP23;HsT17016;SNAP-23;SNAP23A;SNAP23B
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SNAP23 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human SNAP23 (NP_003816.2). |
| Gene ID: | 8773 |
| Swiss prot: | O00161 |
| Molecular weight: | 17kDa/23kDa |
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