Western blot analysis of extracts of various cell lines, using RIN2 antibody (A13798) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
RIN2 Rabbit pAb
Catalog No:AB-A13798
Manufacturer:ABclonal
Synonyms:RIN2;MACS;RASSF4
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RIN2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1). |
Gene ID: | 54453 |
Swiss prot: | Q8WYP3 |
Molecular weight: | 100kDa/105kDa |
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