Western blot analysis of extracts of THP-1 cells, using IRF8 antibody (A13677) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
IRF8 Rabbit pAb
Catalog No:AB-A13677
Manufacturer:ABclonal
Synonyms:IRF8;H-ICSBP;ICSBP;ICSBP1;IMD32A;IMD32B;IRF-8
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | IRF8 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1). |
Gene ID: | 3394 |
Swiss prot: | Q02556 |
Molecular weight: | 48kDa |
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