Prosaptide TX14(A)
Catalog No:CP-PROS-001A
Manufacturer:CPC Scientific
Size:1 mg
Formula:C69H110 N16O26
MWt:1,580
€102,00
Product Name: | Prosaptide TX14(A) |
Category: | Peptides |
Three letter sequence: | Thr-D-Ala- Leu-Ile-Asp- Asn-Asn-Ala- Thr-Glu-Glu- Ile-Leu-Tyr |
One letter sequence: | TaLIDNNATEEI LY |
Description: | This 14-mer prosaptide sequence is derived from the active neurotrophic region in the amino- terminal portion of the saposin C domain. Synthetic peptides derived from this region are biologically active and are named 鈥 prosaptides.鈥 Prosaposin and prosaptides are active on a variety of neuronal cells, stimulating sulfatide synthesis and increasing sulfatide concentration in Schwann cells and oligodendrocytes. This indicates that prosaposin and prosaptides are trophic factors for |
Literature References: | Campana, M. et al. FASEB J. 12, 307 (1998); Hiraiwa, M. et al. Proc. Natl. Acad. Sci. USA 94, 4778 (1997); Taylor, E. et al. Pharmacol. 295, 190 (2000); Calcutt, NA. et al. Anesthesiology 93, 1271 (2000). |
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