RGD-4C
Catalog No:CP-RGDP-008A
Manufacturer:CPC Scientific
Size:1 mg
Formula:C42H60N 14O16S4
MWt:1,145
€452,00
Product Name: | RGD-4C |
Category: | Peptides |
Three letter sequence: | Ala-Cys-Asp- Cys-Arg-Gly- Asp-Cys- Phe-Cys-Gly (Disulfide bridge: 2-10 and 4-8) |
One letter sequence: | ACDCRGDCFC G (Disulfide bridge: 2-10 and 4-8) |
Description: | This peptide, a double cyclic peptide, binds preferentially to integrins at sites of tumor angiogenesis and inflammed synovium in-vivo, and can be internalized into targeted cells |
Literature References: | Curnis, F. et al. Cancer Res. 64, 565 (2004); Su, Z. et al. Bioconjug. Chem. 13, 561 (2002); Gerlag, M. et al. Arthritis Res. 3, 357 (2001); Ellerby, H. et al. Nature Med. 5, 1032 (1999); |
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