p53 (17-26), FITC labeled
Catalog No:CP-CANC-017A
Manufacturer:CPC Scientific
Size:1 mg
MWt:1,753
€240,00
Product Name: | p53 (17-26), FITC labeled |
Category: | Peptides |
Three letter sequence: | FITC-LC- Glu-Thr-Phe- Ser-Asp-Leu- Trp-Lys-Leu- Leu-NH2 |
One letter sequence: | FITC-LC- ETFSDLWKLL- NH2 |
Description: | This is amino acids 17 to 26 fragment of p53, fluorescent labeled through an LC spacer. This peptide is the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that come into contact with the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development, FITC (Abs/Em=493 nm/517 nm).. |
Literature References: | Yu, G. et al. PNAS 103, 1227 (2006) Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006) Kanovsky, M. et al. PNAS 98, 12438 (2001). |
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