[Lys(Me2)370]- p53 (361-380); p53K370Me2
Catalog No:CP-CANC-011B
Manufacturer:CPC Scientific
Size:1 mg
MWt:2,204
€374,00
Product Name: | [Lys(Me2)370]- p53 (361-380); p53K370Me2 |
Category: | Peptides |
Three letter sequence: | Gly-Ser-Arg- Ala-His-Ser- Ser-His-Leu- Lys(Me2)- Ser-Lys-Lys- Gly-Gln-Ser- Thr-Ser-Arg- His |
One letter sequence: | GSRAHSSHL- K(Me2)- SKKGQSTSRH |
Description: | p53K370Me2 is derived from amino acid residues 361- 380 of human p53 tumor suppressor protein, with dimethylation at Lys370. This peptide promotes p53 interactions with both p21gene promoters and p53 binding protein 1 (53BP1), activating transcription of p53 target genes |
Literature References: | Egorova, K. Biochem 75, 535 (2010). |
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