[Lys(Me1)373]- p53 (368-393), p53 K373(Me1), biotin-labeled, human
Catalog No:CP-CANC-009B
Manufacturer:CPC Scientific
Size:1 mg
MWt:3,582
€422,00
Product Name: | [Lys(Me1)373]- p53 (368-393), p53 K373(Me1), biotin-labeled, human |
Category: | Peptides |
Three letter sequence: | Biotin-Lys- Gly-Trp-His- Leu-Lys-Ser- Lys(Me1)- Lys-Gly-Gln- Ser-Thr-Ser- Arg-His-Lys- Lys-Leu-Met- Phe-Lys-Thr- Glu-Gly-Pro- Asp-Ser-Asp- NH2 |
One letter sequence: | Biotin- KGWHLKS- K(Me1)- KGQSTSRHKKL MFKTEGPDSD- NH2 |
Description: | This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53. |
Literature References: | Krishnan, S. et al. ChemBioChem 12, 254 (2011) Huang, J. et al. J Biol Chem 285, 9636 (2010). |
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