[Lys(Ac)373]- p53 (368-393), p53 K373(Ac), biotin-labeled, human
Catalog No:CP-CANC-002B
Manufacturer:CPC Scientific
Size:1 mg
MWt:3,481
€411,00
Product Name: | [Lys(Ac)373]- p53 (368-393), p53 K373(Ac), biotin-labeled, human |
Category: | Peptides |
Three letter sequence: | Biotin-Lys- Gly-Gly-His- Leu-Lys-Ser- Lys-Lys(Ac)- Gly-Gln-Ser- Thr-Ser-Arg- His-Lys-Lys- Leu-Met- Phe-Lys-Thr- Glu-Gly-Pro- Asp-Ser-Asp- NH2 |
One letter sequence: | Biotin- KGGHLKSK- K(Ac)- GQSTSRHKKL MFKTEGPDSD- NH2 |
Description: | This peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N- terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage. |
Literature References: | Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001). |
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