PAR-4 (1-6) (human)
Catalog No:CP-PARP-010B
Manufacturer:CPC Scientific
Size:25 mg
CAS No.:225779-44-2
Formula:C28H41N 7O9
MWt:620
€334,00
Product Name: | PAR-4 (1-6) (human) |
Category: | Peptides |
Three letter sequence: | H-Gly-Tyr- Pro-Gly-Gln- Val-OH Trifluoroacet ate salt |
One letter sequence: | GYPGQV |
Description: | This peptide is the amino terminus of the fourth protease- activated receptor (PAR4) after the cleavage at Arg47/Gly48 was tested for its ability to stimulate COS cells expressing PAR4. The peptide readily activated both wild- type and mutant PAR4 (R47A) at 500 碌M, whereas thrombin and trypsin only activate the wild-type PAR4. |
Literature References: | W.-F.Xu et al., Proc. Natl. Acad. Sci. USA, 95, 6642 (1998) H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999) R.Kaufmann et al., J. Cancer Res. Clin. Oncol., 126, 91 (2000) |
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