PACAP-38 (6- 38) (human, chicken, mouse, ovine, porcine, rat)
Catalog No:CP-PACA-008B
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:143748-18-9
Formula:C182H300 N56O45S
MWt:4,025
€300,00
Product Name: | PACAP-38 (6- 38) (human, chicken, mouse, ovine, porcine, rat) |
Category: | Peptides |
Three letter sequence: | Phe-Thr-Asp- Ser-Tyr-Ser- Arg-Tyr-Arg- Lys-Gln-Met- Ala-Val-Lys- Lys-Tyr-Leu- Ala-Ala-Val- Leu-Gly-Lys- Arg-Tyr-Lys- Gln-Arg-Val- Lys-Asn-Lys- NH2 Trifluoroacet ate salt |
One letter sequence: | FTDSYSRYRKQ MAVKKYLAAVL GKRYKQRVKN K-NH2 |
Description: | This peptide is the fragment 6-38 of PACAP, which is a much more potent and selective inhibitor of PACAP- 27-stimulated pituitary adenylate cyclase than PACAP (6-27). Ki values for the inhibition of the enzyme were 7 nM and 150 nM respectively. |
Literature References: | P.Robberecht et al., Mol. Pharmacol., 42, 347 (1992) P.Robberecht et al., Eur. J. Biochem., 207, 239 (1992) F.Ohno et al., Regul. Peptides, 126, 115 (2005) P. Robberecht, P. Gourlet, P. De Neef, M-C. Woussen-Colle, M-C. Vandermeers- Piret, A. Vandermeers, and J. Christophe, Eur. J. Biochem., 207, 239 (1992). (Original) A. Vandermeers, S. Vandenborre, X. Hou, P. De Neef, P. |
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