Neuropeptide S (rat)
Catalog No:CP-NEUP-012B
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:412938-75-1
Formula:C95H160 N34O27
MWt:2,211
€298,00
Product Name: | Neuropeptide S (rat) |
Category: | Peptides |
Three letter sequence: | Ser-Phe-Arg- Asn-Gly-Val- Gly-Ser-Gly- Val-Lys-Lys- Thr-Ser-Phe- Arg-Arg-Ala- Lys-Gln Trifluoroacet ate salt |
One letter sequence: | SFRNGVGSGN KKTSFRRAKQ |
Description: | This peptide is a modulator of arousal and possibly anxiety- related behaviour. It acts by activating its cognate receptor (NPSR) and inducing mobilization of intracellular Ca2+. Central administration of NPS induced wakefulness and reduced slow wave and REM sleep in rats. These peptides represent potential lead compounds for the treatment of sleep and anxiety disorders. |
Literature References: | Y.-L.Xu et al., Neuron, 43, 487 (2004) N.Okamura and N.K.Reinscheid, Stress, 10, 221 (2007) K.Domschke et al., Mol. Psychiatry, 16, 938 (2011) |
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