IGF-I (1-3)
Catalog No:CP-ILGF-003A
Manufacturer:CPC Scientific
Size:250 mg
CAS No.:32302-76-4
Formula:C12H19N 3O6
MWt:301
€112,00
Product Name: | IGF-I (1-3) |
Category: | Peptides |
Three letter sequence: | Gly-Pro-Glu |
One letter sequence: | GPE |
Description: | This N-terminal tripeptide of IGF-I facilitated the in vitro release of acetylcholine with a several hundredfold higher potency (10- 10 – 10-6 M) than intact IGF-I (4 路 10-8 M), whereas truncated IGF-I lacking the tripeptide GPE, did not show any significant effect. This raises the possibility that GPE may be the active site of IGF-I. – Although the precise mode of action of GPE is still unknown, another study suggests that local administration of GPE is neuroprotective after brain HI injury via |
Literature References: | L.Nilsson- Hakansson et al., NeuroReport, 4, 1111 (1993) S.V.Sizonenko et al., Brain Res., 922, 42 (2001) J.Guan et al., Neuropharmacolo gy, 47, 892 (2004) D.Aguado-Llera et al., Neuroreport, 15, 1978 (2004) S.Shapira et al., Neurosci. Lett., 454, 53 (2009) |
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Manufacturer:ABclonal
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Expression Host:HEK293 cells
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