[Lys(Me3)27]- Histone H3 (21-44), biotin- labeled
Catalog No:CP-HIST-058B
Manufacturer:CPC Scientific
Size:1 mg
MWt:2,902
€327,00
Product Name: | [Lys(Me3)27]- Histone H3 (21-44), biotin- labeled |
Category: | Peptides |
Three letter sequence: | Ala-Thr-Lys- Ala-Ala-Arg- Lys(Me3)- Ser-Ala-Pro- Ala-Thr-Gly- Gly-Val-Lys- Lys-Pro-His- Arg-Tyr-Arg- Pro-Gly- Lys(Biotin) |
One letter sequence: | ATKAAR- K(Me3)- SAPATGGVKK PHRYRPG- K(Biotin) |
Description: | This peptide is the fragment of Histone H3 (21-44) tri- methylated at Lys27 with an additional C- terminal Lys and biotinylation on the epsilon side chain of this Lys. Tri- methylation of Lys27 promotes Polycomb protein (Pc)- chromatin association and is associated with heterochromatin assembly and gene silencing. |
Literature References: | Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007); Min, J. et al. Genes Dev 17, 1823 (2003). |
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