Charybdotoxin
Catalog No:CP-CHAT-001C
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:95751-30-7
Formula:C176H277 N57O55S 7
MWt:4,296
€1.401,00
Product Name: | Charybdotoxin |
Category: | Peptides |
Three letter sequence: | Glp-Phe-Thr- Asn-Val-Ser- Cys-Thr-Thr- Ser-Lys-Glu- Cys-Trp-Ser- Val-Cys-Gln- Arg-Leu-His- Asn-Thr-Ser- Arg-Gly-Lys- Cys-Met-Asn- Lys-Lys-Cys- Arg-Cys-Tyr- Ser(Cys7 and Cys28/Cys13 and Cys33/Cys17 and Cys35 Bridge) |
One letter sequence: | Glp- FTNVSCTTSKE CWSVCQRLHN TSRGKCMNKK CRCYS(Cys7 and Cys28/Cys13 and Cys33/Cys17 and Cys35 Bridge) |
Description: | The peptide was found in the venom of the scorpionc Leiurus quinquestriatus, is a Ca2+-activated K+ channel blocker. |
Literature References: | G.Gimenez- Gallego et al., Proc. Natl. Acad. Sci. USA, 85, 3329 (1988) R.MacKinnon and C.Miller, Science, 245, 1382 (1989) N.A.Castle et al., Trends Neurosci., 12, 59 (1989) T.R.Werkman et al., Neuroscience, 50, 935 (1992) T.R.Jones et al., J. Appl. Physiol., 74, 1879 (1993) C.Miller, Neuron, 15, 5 (1995) K.G.Chandy et al., Trends Pharmacol. Sci., 25, 280 (2004) |
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