Mca-Amyloid b/A4 Protein Precursor770 (667-676)-Lys(DNP)-Arg- Arg amide
Catalog No:CP-AMYD-110A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C87H129 N27O28S 1
MWt:2,033
€83,00
Product Name: | Mca-Amyloid b/A4 Protein Precursor770 (667-676)- Lys(DNP)-Arg- Arg amide |
Category: | Peptides |
Three letter sequence: | Mca-Ser-Glu- Val-Lys-Met- Asp-Ala-Glu- Phe-Arg- Lys(DNP)- Arg-Arg-NH2 |
One letter sequence: | Mca- SEVKMDAEFR- K(DNP)-RR-NH2 |
Description: | Fluorescent peptide substrate that contains the wild- type amyloid precursor protein (APP) 尾-secretase cleavage site. It is used for assaying 尾- secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). Studies reveal that TOP is a potential 尾- secretase candidate and is involved in the processing of APP in vivo. |
Literature References: | H. Koike et al., J. Biochem. , 126, 235 (1999) |
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