(Asn670,Leu671)- Amyloid b/A4 Protein Precursor770 (667-675)
Catalog No：CP-AMYD-047A
Manufacturer：CPC Scientific
Size：1 mg
Formula：C44H66N 10O18
MWt：1,023
€77,00
| Product Name: | (Asn670,Leu671)- Amyloid b/A4 Protein Precursor770 (667-675) |
| Category: | Peptides |
| Three letter sequence: | Ser-Glu-Val- Asn-Leu-Asp- Ala-Glu-Phe |
| One letter sequence: | SEVNLDAEF |
| Description: | Peptide substrate that corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer’s disease, henceforth referred to as the “Swedish “mutation. The peptide has been used for assaying cleavage at leucine- aspartate by cathespin G and chymotrypsin, whereas neither cathepsin B, D, nor L generated any products. |
| Literature References: | M. Citron et al., Nature , 360, 672 (1992); M. Mullan et al., Nature Gen ., 1, 345 (1992); S.R. Sahasrabudhe et al., J. Biol. Chem. , 268, 16699 (1993) |
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