(Asn670,Leu671)- Amyloid b/A4 Protein Precursor770 (667-675)
Catalog No:CP-AMYD-047A
Manufacturer:CPC Scientific
Size:1 mg
Formula:C44H66N 10O18
MWt:1,023
€77,00
Product Name: | (Asn670,Leu671)- Amyloid b/A4 Protein Precursor770 (667-675) |
Category: | Peptides |
Three letter sequence: | Ser-Glu-Val- Asn-Leu-Asp- Ala-Glu-Phe |
One letter sequence: | SEVNLDAEF |
Description: | Peptide substrate that corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer’s disease, henceforth referred to as the “Swedish “mutation. The peptide has been used for assaying cleavage at leucine- aspartate by cathespin G and chymotrypsin, whereas neither cathepsin B, D, nor L generated any products. |
Literature References: | M. Citron et al., Nature , 360, 672 (1992); M. Mullan et al., Nature Gen ., 1, 345 (1992); S.R. Sahasrabudhe et al., J. Biol. Chem. , 268, 16699 (1993) |
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