Melittin
Catalog No:CP-PKCP-018A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C131H229 N39O31
MWt:2,847
€113,00
Product Name: | Melittin |
Category: | Peptides |
Three letter sequence: | Gly-Ile-Gly- Ala-Val-Leu- Lys-Val-Leu- Thr-Thr-Gly- Leu-Pro-Ala- Leu-Ile-Ser- Trp-Ile-Lys- Arg-Lys-Arg- Gln-Gln-NH2 |
One letter sequence: | GIGAVLKVLTT GLPALISWIKRK RQQ-NH2 |
Description: | 26-residue polypeptide isolated from bee venom that binds calmodulin in a Ca2+ dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50 = 5-7 m M) by binding to the catalytic domain in a Mg-ATP sensitive manner. IC50 of 1-4 渭M. |
Literature References: | Raynor et al., J. Biol. Chem ., 266, 2753 (1991); Schweitz, Toxicon , 22, 308 (1984) |
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