Orexin B, human
Catalog No:CP-OREX-002A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C123H212 N44O35S 1
MWt:2,898
€113,00
Product Name: | Orexin B, human |
Category: | Peptides |
Three letter sequence: | Arg-Ser-Gly- Pro-Pro-Gly- Leu-Gln-Gly- Arg-Leu-Gln- Arg-Leu-Leu- Gln-Ala-Ser- Gly-Asn-His- Ala-Ala-Gly- Ile-Leu-Thr- Met-NH2 |
One letter sequence: | RSGPPGLQGR LQRLLQASGNH AAGILTM-NH2 |
Description: | Hypothalamic neuropeptide that regulates feeding behavior and significantly augments food intake in a dose- dependent manner when a bolus is administered intracerebroventricul arly. After a 48-hour fast, hypothalamic prpro-orexin mRNA level is up-regulated 2.4. The discovery of orexins and their receptors may provide a novel molecular basis for understanding the role of the lateral hypothalamic areas in the regulation of energy homeostasis. |
Literature References: | M.W. Schwartz, Nature Med., 4, 385 (1998); T. Sakurai et al., Cell, 92, 573 (1998) |
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