MMP Substrate IV, Fluorogenic
Catalog No:CP-MMPS-022B
Manufacturer:CPC Scientific
Size:1 mg
Formula:C99H144 N28O20S 1
MWt:2,079
€160,00
Product Name: | MMP Substrate IV, Fluorogenic |
Category: | Peptides |
Three letter sequence: | DABCYL- GABA-Arg- Pro-Lys-Pro- Val-Glu-Nva- Trp-Arg- Glu(EDANS)- Ala-Lys-NH2 |
One letter sequence: | Dabcyl-GABA- RPKPVE-Nva- WR-Glu(Edans)- AK-NH2 |
Description: | Selective fluorogenic matrix metalloproteinase (MMP) substrate with the following Kcat/Km value for MMP-3 (Stromelysiin-1) is 29.0 M-1s-1, for MMP-13 13.0 M-1s- 1, and for MMP-9 7.5 M-1s-1 (at pH = 7.5, 25掳C). The fluorescence increase is measured using an wavelength of 360 nm and an emission wavelength of 490 nm. No activity against this substrate could be measured with MMP- 1, MMP-7, and MMP-8. |
Literature References: | Beekman, B., et al., 1997. FEBS Lett 418, 305. |
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