MMP Substrate III, Fluorogenic
Catalog No:CP-MMPS-021B
Manufacturer:CPC Scientific
Size:1 mg
Formula:C63H88N 16O14S1
MWt:1,326
€160,00
Product Name: | MMP Substrate III, Fluorogenic |
Category: | Peptides |
Three letter sequence: | DABCYL- GABA-Pro- Gln-Gly-Leu- Glu(EDANS)- Ala-Lys-NH2 |
One letter sequence: | Dabcyl-GABA- PQGL- Glu(Edans)-AK- NH2 |
Description: | Highly soluble fluorogenic matrix metalloproteinase (MMP) substrate with the following kcat/km values (at pH 7.6, 37 掳C): 619.0 M-1s-1 for MMP-2, 209.0 M-1s- 1 for MMP-9, 40.0 M-1s-1 for MMP-3, 21.0 M-1s-1 for MMP-1. The fluorescence increase is measured using an wavelength of 340 nm and emission wavelength of 485 nm. The relative high emission wavelength of EDANS allows convenient measurement of MMP activity in complex biological media like synovial fluid and culture |
Literature References: | B. Beekman, et al., FEBS Lett, 390, 221 ( 1996). |
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