MMP-13Substrate, Fluorogenic
Catalog No:CP-MMPS-016B
Manufacturer:CPC Scientific
Size:1 mg
Formula:C51H65N 13O15
MWt:1100.2
€113,00
Product Name: | MMP-13 Substrate, Fluorogenic |
Category: | Peptides |
Three letter sequence: | Mca-Pro- Cha-Gly- Nva-His-Ala- Dap(DNP)- NH2 |
One letter sequence: | Mca-P-Cha-G- Nva-HA- Dap(DNP)-NH2 |
Description: | Specific fluorogenic substrate for collagenase-3 (MMP) with a kcat/Km value of 1.09鈥106 M-1s-1 (pH = 7.5, T = 25 掳 C, substrate concentrations: 0.7 and 1.4 渭M (S<<Km), determined for activated recombinant collagenase-3) . Collagenase-3 hydrolyzed this substrate 70-100 fold more efficiently than collagenase-2 (MMP- 8) and collagenase- 1(MMP-1). |
Literature References: | V. Knauper, et al., J. Biol. Chem. 271, 1544 (1996) |
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