MMP-2Substrate, Fluorogenic
Catalog No:CP-MMPS-006A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C49H68N 14O15
MWt:1093.2
€77,00
Product Name: | MMP-2 Substrate, Fluorogenic |
Category: | Peptides |
Three letter sequence: | Mca-Pro- Leu-Ala-Nva- Dap(DNP)- Ala-Arg-NH2 |
One letter sequence: | Mca-PLA-Nva- Dap(Dnp)-AR- NH2 |
Description: | Sensitive substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. When cleaved at the Gly- Leu bond it separates the highly fluorescent Mca group from the efficient 2,4- dinitrophenyl quencher and results in the increase of fluorescence intensity. The kcat/km value for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7鈥105 and 6.3鈥105 M-1s-1, respectively. |
Literature References: | G. Murphy, et al., J. Biol. Chem. 269, 6632 (1994). |
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Manufacturer:CPC Scientific
Size:0.5 mg
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