Exendin-3
Catalog No:CP-EXED-005A
Manufacturer:CPC Scientific
Size:0.5 mg
Formula:C184H282 N50O61S 1
MWt:4,203
€148,00
Product Name: | Exendin-3 |
Category: | Peptides |
Three letter sequence: | His-Ser-Asp- Gly-Thr-Phe- Thr-Ser-Asp- Leu-Ser-Lys- Gln-Met-Glu- Glu-Glu-Ala- Val-Arg-Leu- Phe-Ile-Glu- Trp-Leu-Lys- Asn-Gly-Gly- Pro-Ser-Ser- Gly-Ala-Pro- Pro-Pro-Ser- NH2 |
One letter sequence: | HSDGTFTSDLS KQMEEEAVRLF IEWLKNGGPSS GAPPPS-NH2 |
Description: | A new member of the Glucagon superfamily that was originally isolated from the venom of the lizard, Heloderma Horridum. At low concentrations, it interacts with putative exendin receptors causing an increase in pancreatic acinar cAMP, while at higher concentrations it interacts with VIP receptors to stimulate an increase in cellular cAMP and amylase release. |
Literature References: | J. Eng et al., J. Biol. Chem., 267, 7402 (1992) |
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