Z-DEVD-AMC
Catalog No：CP-CASP-085A
Manufacturer：CPC Scientific
Size：0.5 mg
Formula：C36H41N 5O14
MWt：768
€18,00
| Product Name: | Z-DEVD-AMC |
| Category: | Peptides |
| Three letter sequence: | Z-Asp-Glu- Val-Asp-AMC |
| One letter sequence: | Z-DEVD-AMC |
| Description: | AMC (7-amino-4- methylcoumarin) derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm. Caspase-3 and caspase-7 substrates |
| Literature References: | Koeplinger KA, et al. (2000). Protein Expr Purif 18, 378-87; Garcia-Calvo M, et al. (1998). J Biol Chem 273, 32608-13; Thornberry NA, et al. (1997). J Biol Chem 272, 17907- 11; Rano TA, et al. (1997). Chem Biol 4, 149-55; Margolin N, et al. (1997). J Biol Chem 272, 7223- 8; Mizushima N, et al. (1996). FEBS Lett 395, 267-71; Faubion WA, et al. (1999). J Clin Invest 103, 137- 45. |
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