Caspase-1 Substrate V, Fluorogenic
Catalog No：CP-CASP-027B
Manufacturer：CPC Scientific
Size：1 mg
CAS No.：[189696-01-3]
Formula：C53H64N 10O19
MWt：1,145
€113,00
| Product Name: | Caspase-1 Substrate V, Fluorogenic |
| Category: | Peptides |
| Three letter sequence: | Mca-Tyr-Val- Ala-Asp-Ala- Pro- Lys(DNP) |
| One letter sequence: | Mca-YVADAP- Lys(DNP) |
| Description: | Highly fluorescent substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of this substrate at position P1 Asp causes continuous fluorescent assay monitored at emission wavelength of 393 nM. Furthermore, caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. |
| Literature References: | M. Enari et al., Nature, 380, 723 (1996) |
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